Ultrasound assisted Mizoroki–Heck reaction catalyzed by Pd/C: Synthesis of 3-vinyl indoles as potential cytotoxic agents

Palladium-catalyzed synthesis of N-vinyl pyrroles and indoles.

A stereospecific palladium-catalyzed N-vinylation of azaheterocycles with vinyl triflates is described. Cyclic and acyclic vinyl triflates along with nonnucleophilic azaheterocycles were found to be substrates for this palladium-catalyzed synthesis of N-vinyl pyrrole and indole derivatives.

synthesis of novel series of coumarins as potential cytotoxic agents

[BMIm]HSO4 as a Green and Highly Efficient Catalyst for One-pot Synthesis of 3-Substituted Indoles under Ultrasound Irradiation

A practical and green synthesis of 3-substituted indoles is reported via three-component coupling reaction of indoles, aldehydes and N-methylaniline in the presence of the acidic ionic liquid 1-butyl-3-methylimidazolium hydrogen sulfate ([BMIm]HSO4) under ultrasound irradiation at room temperature. The significant features of this procedure are high yields of the products, simple work-up, opera...

Microwave Assisted Synthesis of N-Benzylenaminones Catalyzed by Chloroacetic acid

Benzylaminoalkenones and benzylaminoalkenoates 3 were synthesized from reaction of benzylamine with corresponding 1,3-diketones and 1,3-ketoesters in the presence of catalytic amount of chloroacetic acid under microwave radiation. This method offers several advantages including high yield of products, recyclable of the catalyst and easy experimental work-up procedure.

Gold-catalyzed synthesis of tetrahydrocarbazole derivatives through an intermolecular cycloaddition of vinyl indoles and N-allenamides.

A gold-catalyzed formal [4+2] cycloaddition of vinyl indoles and N-allenamides leading to tetrahydrocarbazoles is described. Moreover, new multicomponent reactions of vinyl indoles with two allene molecules are reported.